Born at Chittagong (British India, present Bangladesh) on the 15th of May, 1838, Dr. Medlycott, had a distinguished educational career in India and later in the Propaganda Fide College, Rome, where he took his Ph.D. Ordained Priest on 17 March 1861, he was nominated titular Bishop of Tricomia and Vicar Apostolic of Trichur on 13 September 1887, consecrated Bishop on 11 December 1887, by H.E. Mgr. Aiuti, the Delegate Apostolic and took charge of the Vicariate on 18 December 1887. He led the Vicariate till 1896.
Dr. Medlycott spent his last days in Bangalore where he breathed his last on 4 May 1918. His mortal remains were brought from Bangalore and re-interred first in the Dolours Church, Trichur on 4 May 1945 and later in the crypt of the Lourdes Cathedral, Trichur on 19 December 1950 by Mar George Alapatt.