Born on 11 February 1900 at Karanchira, Dr. George Alapatt had his college education at St. Thomas' College, Trichur and his ecclesiastical education at the Propaganda Fide College, Rome, where he took his PhD and S.T.D. He was ordained priest on 17 December 1927 and nominated Bishop of Trichur 11 March, 1944. He was consecrated Bishop on 1 May, 1944 at Trichur by H. Ex. Dr. Leo P. Kierkels, the Apostolic Delegate, and on the same day he took charge of the Eparchy. He attended all the four Sessions of the Vatican Council II (1962 - 1965).
In 1967 the University of Detroit conferred on him the Honorary Degree of Doctor in Human Letters. In 1969, on the occasion of his Episcopal Silver Jubilee, H. H. Pope Paul VI nominated him as "assistant at the Papal Throne". He retired on 4 June 1970, and was appointed titular bishop of Irenopolis in Isauria. He continued as administrator of the Eparchy till 16 August 1970.
While he was taking rest at Sarto Sadan, Karanchira, on 6 November, 1973, he slept in the Lord and in accordance with his desire his body was interred at St. Pius X Chapel in Karanchira. On 10 Feb 1999 a part of his mortal remains was brought from Karanchira and interred in the crypt of the Metropolitan Cathedral, Trichur.